Scientists Discover the Holy Grail of Longevity? Blocking IL-11 To Reverse Aging & Extend Healthspan

Professor Stuart Cook talks about blocking Interleukin-11 reverses multiple hallmarks of aging. This therapy may have the similar effects of combination of rapamycin, metformin and senolytics. The IL-11/ERK/mTOR axis of senescence is a therapeutic target for extending mammalian healthspan.

https://www.nature.com/articles/s41586-024-07701-9
Inhibition of IL-11 signalling extends mammalian healthspan and lifespan

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9386112/
IL11 stimulates ERK/P90RSK to inhibit LKB1/AMPK and activate mTOR initiating a mesenchymal program in stromal, epithelial, and cancer cells

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10754292/
Understanding interleukin 11 as a disease gene and therapeutic target

https://neurosciencenews.com/inflammation-il11-longevity-26458/
Blocking Inflammation Protein Extends Lifespan

https://www.telegraph.co.uk/news/2024/07/17/scientists-find-anti-ageing-holy-grail-that-can-stop-cancer/

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DISCLAIMER: The information and opinions expressed in this video are for informational purposes only and are not intended to be a substitute for professional medical advice, diagnosis, or treatment. Please consult with your doctor or other qualified health provider before start taking any supplements.



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