Selenium: How Much Is Optimal For Health?

How to reduce e hydrogen peroxide, I think that's the key

HIi like your videos. It would be nice to see the conculsion or results at the end of the video. I do watch and can understand the whole video but sometime just like to get the end results, summary or conclusion.

i had just bought 200mcg selenium capsules... RIP... will buy 100mcg ones next (only getting 60mcg from my diet daily)

Great stuff. Lowest all-cause at 1.3µmol though? That's some knicking point but some people benefited at higher levels and some didn't. So depending on other factors you might not want to go higher, but if you fixed other factors, you very much ought!

What do you think about Tung Oil or lipid selenium?

Great detail on selenium. I am a convert.

Very interesting and useful! Great job! But I find it very curious that blood glucose should decrease while uric acid increases with rising selenium intake. I thought these 2 values are correlated, ie rise/fall together? Also, is it possible that people with premature graying hair might benefit from more selenium, since hydrogen peroxide is implicated in hair graying?

Hello Mike I'm trying to get into supplements business but I want to learn first about how the whole thing works,hope you make videos on all the Vitamins,Minerals and Other Nutrients so we can all learn in depth on how they all work together to give us optimal health.

Dr Lustgarten,
is 200 mcg , ok

Just discovered my selenium is 134 / 1,69 (without supplementation) and freaking out........

Going to try 1000 mg daily as I have one tooth amalgam (mercury) filling.

Can you please add the northwest soils and waters have been found to be selenium toxic. These states also have high rates of als diagnosed. There is concern over spread through rainfall. Research also expects a rise in als diagnosed. Foods and water may contain more selenium than expected.

Had been taking 200mcg daily for about three months and found a significant reduction in glucose, but also a weight gain. It appears some of the excess glucose was converted to fat of some type. Also experienced smelly urine towards the end of this period. I did not know what was a possible cause, until now. I'm not clear on whether smelly urine is a bad thing, besides being unpleasant. My kidneys are tested reguarly and show no issues. On the other hand, I also saw a reduction in inflamation and skin infections, both of which I am prone to get. One area in particular has been a painful recurring issue off and on for years and this was the only change that worked. Very happy with that. But 200mcg a day on top of dietary silenium is probably too much. I will cut the dose in half and give it another threee months.

Please do one on Milk Thistle! This1 was great.

Just to update, I stopped eating the Brazils, checked daily supplement and found it contained 200mcg! so stopped that for 7 days. I didn't stop eating steak and eggs but did stop the sardines. Toe swelling reduced within 5 days, not visible after 7 days. Stinky pee reduced within same time frame and now 'normal' levels. I have found real difficulty in sleeping for periods longer than 3 hours though. Going back to 200mcg every 2 days and staying off the Brazil nuts now until clear and stable.... thanks again.

Brilliant work, many thanks. It's given me some strong clues for some symptoms developed over the last few months, particularly around high uric acid levels (stinky pee etc)... just the last couple of weeks have developed gout like symptoms with swollen itchy toes (just on one foot oddly).. Compared to rda's I've been off the scale! Maybe 50g per day in Brazil's with dark low sugar chocolate, a tin of sardines per day some days, red meat (inc pork) twice a day and at least three eggs per day.... every day. Damn I need to reduce and detox asap..... thanks again....

Which supplement form of selenium would you recommend taking if you cannot get it from diet?

Hi Michael. How do you avoid BPA inside the sardine tins? Or is BPA something that is overblown? Or do you eat 'em fresh? In Morocco you can get fresh grilled sardines for something like a dollar.. maybe two?

Thanks Mike! Great video! Do you take breaks in your Selenium diet?

Great video. Thankyou.

As always, great video. The main issue I have with my daily selenium consumption is the huge variability in selenium content per Brazil nut. The “average” Brazil nut is reportedly around 5g, but the selenium content per nut can vary very dramatically. I can track my selenium intake from other dietary sources to a fairly close number. However, with 1-2 Brazil nuts added in, the total Selenium intake can be all over the place. From too low to too high.

The best video on selenium

Thank you for your detailed research and analysis. I just got my selenium blood lab results back and they are too high. I will be cutting back now.

So for a 55 yr old, what is the recommended dose? TY
Bentothiamine is great for Glucose...see SugarMD

You rock Dr. Lutsgarten!

Thank you for your work!

Outstanding as always, and particulalry timely as I've been trying to decide whether to increase my Se intake to counter subclinical hypothyroidism. Your biomarker selection is comprehensive. One curiosity is the glucose finding. How would you reconcile this with the fact that SELENOP excess is associated with insulin resistance? A possible hidden factor in overall mortality is that selenide is evidently more toxic to cancer cells than to normal cells.

We use peroxide to clean cells, but its a cycle

Huh. Lot to learn here...
Is there a “rule of thumb” number of how much it costs/gives to have Selenium in the right range, vs. too low or too high? Are we talking months? Years?
What I am going after is very rough estimates, order of magnitude-stuff. For example, I have heard about 5 years for Metformin. I have also heard higher numbers for Metformin, but for me, knowing that we are potentially in the “year range” makes it something that is very high on my prioritization list.

Just checked Selenium levels in food, 4 Eggs for breakfast and 150+g meat for dinner gets me over 120 mcg, so close enough I guess...

Informative! Thank you.

Thanks Mike, I've been supplementing and will now lower the dose for sure. Great info, thanks for sharing.

Do you have an example of your current nutrition plan and rational behind the quantities and choices? Maybe even future modifications?

It would be really interesting to see a video tutorial on blood tests and how to diy read/“fix” them for optimal health, so that the average person can improve.
🙏thanks

Thank you very much for sharing this Michael!

Very nice! Thank you for sharing 🙏💪💪❤️

very nice, thank you for the great work

Wonder info. Can’t get enuf of your videos. Great job👍👍

Can you give me any suggestions on how to fix my cervicogenic headache I've had for a few months now? Otherwise fit and healthy.

Digestive impairment may mean that dosage of selenium needs to be increased.

I also wonder if timing of the selenium containing meal makes a difference? Some compounds are better used by the body based on circadian rhythms. Also there is a synthetic relationship between some micronutrient and anti oxidants as well as macros. Is there anything that improves bioavailability and functionality?

Seems that depending on calories, either brazil nuts or some form of supplementation may be needed if low calorie diet to reach optimal levels. But if high calorie depending on foods perhaps supplementation need be avoided.

inhibiting IGF-1 signaling and the methionine restriction effects of selenium are very promising/ advantageous.
Might be able to relax on the fasting and not worry about meat consumption as much.

What kind of selenium did you use? L-selenium metionine, selenite.or....?

This was really good info. A lot of other channels just tell you selenium is important, but without finding an optimal dose, it's hard to get the most out of their recommendations. Combining your data with the studies is a practical and convincing way to get the answer. Thanks for the video!

Did you decide to reduce nuts or sardines intake?

P.S you should look at Alpha Ketoglutarate, Calcium Alpha Ketoglutarate, Creatine Alpha Ketoglutarate. All of the AKG and what it can be bound to - the effects.

Selenium is required for proper Thymus function and T cell production. Too little means faster thymic involution, too much means faster thymic involution.

Would really like to know the optimal amount for human thymic maintenance.

Most in depth and to the point info!✌️thanks!