hsCRP: What's Optimal, Which Factors May Reduce It?

In an other video I heared you mention fat intake inversely being correlated with hs-CRP. Does that correlation no longer apply and are just foods in this video correlated with hs-CRP?

Great explanation with help of Statistics. I understand very well as i am from Statistics background. Great work keep it up.

How many reps/sets do you do when you do resistance training?

Hi doc, you are phenomenal. I really appreciate your work and effort. Thank you so much.

Thanks for the video. Very informative. Since hsCrp is only one biomarker for inflammation which do you give more weight to? Thanks.

are you telling me that broccoli and spinach are pro inflamatori foods,....... are pro hsCRP ???

I dont like the conclusions from food correlations. If low mortality is correlated with low hsCRP and low hsCRP is correlated with certain foods, then the link between that food and mortality is very, very weak, not to mention causality. Brokkoli for example i usually considered healthy because of other ingredients.

if u want another soap tasting super spice like turmeric try black cumin (nigella sativa) in case uhavent considered it yet
its also got some solid science backing its efficacy

Please confirm...as its contrary to all nutritional advice...
That broccoli & bananas & cheese & Spinach increases inflamation and intake should be avoided/minimised.
(As shown by your diagram at 5-minute mark.)

Great work and some very interesting surprises! I was shocked to see broccoli raising CRP. This would seem to collide rather soundly with copious recent data suggesting a multitude of anti-inflammatory/brain-protective/anticancer properties for the sulforaphane/myrosinase combo (esp from broccoli sprouts) as well as epidemiologic data indicating health benefits from broccoli in general. Do you have any thoughts on this?

I don’t see meats ?

your work is incredible useful. it motivated me to check for some key parameters (currently i cannot afford extensive testing as you do), and track food as well. Especially helpful are your depictions of the age related changes of the targeted parameters. Thank you so much!
(I have sth more to say but YT removes it because it is too long :( )

Is hsCRP fundamentally different from plain old CRP? Is it measuring something different? My blood tests usually have 2 digits -- like 1.7 or 3.9 or something like that. The blood test result print outs just say CRP. At one hospital, it specifically says hsCRP and has more digits of significance, like 1.732 (maybe only 1.73). But since the number bounces around so much, I don't see the point of having the extra digits. So what's the point of hsCRP vs regular old CRP?

Very informative. Thanks for your efforts

Same for me: a CRP of 0.4 with a moderate & vigorous exercise combo in 3 consecutive tests. Down to 0.3 when I had a knee injury which forced me to do only moderate exercise.

If there are about 9.54 grams of turmeric powder in a tablespoon, then are you consuming about a teaspoon of turmeric a day?

your videos are incredibly well made, excellent work

Hi Michael, is this the reason you switched from Spinach to Collards? Tx, jt

How much exercise is too much is always a question I'm pondering. It feels like there may be a lower ceiling to benefits for cardio than there is for strength. Looking forward to a future video on this subject! 🙏

Nice video. The black pepper may correlate simply because it increases absorption of the tumeric as a CYP3A4 inhibitor.
Also, I wonder if the broccoli and spinach you had been eating that raised CRP were raw, steamed or cooked? As cooking or steaming makes those particular foods 'healthier' in some ways.

Lastly as far as longevity, we've all seen the studies that moderate exercise, is better than zero exercise, which is better than too much exercise such as marathon trainers. Also huge bodybuilders don't live long at all, so it seems one must decide whether they want to eat a lot of protein and get jacked, or be a long-lived dweeb at the beach.

My mom is 84.5 years old and she had a hsCRP test a couple of weeks ago and it was 0.4mg/L. I plugged this into the Levine Biological Age Calculator along with her other bloodwork test results and it shows that she has now aged minus 18 years during the last 4 years. She had been a type 2 diabetic for 12 years prior to that and she had been aging prematurely, but thankfully that trend has been reversed. Her physician said that she was very impressed with the 0.4 number for her hsCRP.

wonder if vanilla bean can be generalised to all beans

It is interesting that broccoli correlates with CRP. It is such a healthy vegetable. In any case, for me, CRP significantly declined when I significantly increased the intake of vegetables and spices. I need to double-click on which vegetables and spices may be causing the decline. Also, improved body composition may have had an impact on the CRP decline.

The active anti-inflammatory molecule in Turmeric is Curcumin. This is not readily absorbed unless accompanied by black pepper (peperine) or fat.
I noticed that black pepper was also listed. This suggests it is the Curcumin/peperine molecule that is active in reducing HsCRP.

Thank you for all the time you spend on the health topic. A problem with assuming broccoli to be a cause for higher hsCRP is the fact that Bryan Johnson(Blueprint) is eating 16.5 lb of broccoli each month and his hsCRP value is 0.20. My general feeling about food and supplements is that is is a personal complex optimization problem.

Interesting to see the difference between broccoli and collards. They are just different cultivars of the same species. I wonder if there were differences in how they were prepared and if that in part might have accounted for the different R values.

So eat strawberries with your banana, and mushrooms with your broccoli, and you're all good...

Excellent video as always, you have the key. Keep up your insight that makes more sense than many others. Thank you again!

Thanks for the video. Can you do this type of video for all biomarkers?

My CRP is always ultra-low but I'm always concerned about my glycation levels...

Depending on what stayed on your plate and what not, the tininess of the amounts involved, I see accurate measuring of black pepper most challenging. I would have expected for this to go in the other direction too.

IT IS SCHOCKING WHAT HE SAYS THAT BROCOLLI HAS HIGHER CRP BUT THE ANTI AGING EXPERT B JONSON SAYS TO EAT BROCCLI AND HERE HE SAYS IT IS BAD OH MY GOSH ... WHAT TO BELIEVE ...

THERE IS NO CLINICAL EVIDENDE THAT TURMERIC HAS AHTIAGING BENEFITS ..

Damn new video and it's wednesday, what a treat lol

Many thanks for another great video. Didn't know that turmeric had such a negative correlation with hCRP. Also didn't know venalla bean had a positive correlation. I'm going to stop using vanella flavored protein powder and see if my hCRP decreases. It used to be 0.5 before I started with the Vanilla protein powder and now it's 1.0

Hey Michael, a small critique here: but the video seems to be very low volume, had to turn my speakers up all the way to be able to hear you.

But other than that, love your content, keep it coming, brother!

Isn't hsCRP correlated with CVD? If so, it's a good idea to lower it. How does it correlate with NAD+ level?

Just a word of caution, i´ve had infections with a very low CRP

Thx Prof.LUSTGARTEN for this another featured presentation.

Intresting , and also intriguing to see that a certain volume of physical activity could be inflammatory.

As for me , during the last Ramadan (dry fasting) I stopped any physical exercise with a minimal activity, eating (1 or 2 meals a day) a tasty cuisine rich in fish,fruits,vegetables, good fats and also as always in turmeric ( in addition to numerous other herbs and spices , sometimes maybe as potent as turmeric) , switched from drinking coffee to green tea. At the end of Ramadan my hsCRP dropped from 3 to O.01 mg/dl and my Apo B was 66.

So, I am excited to see that you are going to address a hot topic rarely raised elsewhere : "Is the amount of physical activity that optimize fitness different from the amount that optimize longevity". My Heart rate is already in the range 55-57 bpm.

I love this new format of showing all the correlations! I was definetly eating much more brocoli than you so I may play with the amount to see if I too have a correlation there.

Can you make sense of the foods that are supposed to be healthy but clearly show a higher hsCRP? like spinach i guess has a ton of oxalates, but so do almonds and turmeric. Broccoli has sulforaphane so maybe the hormetic stress is too much and just a smaller dose needed if one at all?